May 2020 – Annaba Biotech News

Gastro-oesophageal reflux disease symptoms and associated risk factors among medical students, Saudi Arabia.

Gastro-oesophageal reflux disease (GERD) is a typical gastrointestinal disease worldwide that’s associated with impaired high quality of life and greater risk of issues.

The identification of risk factors is critical for preventive measures. The purpose of this research is to judge the prevalence of GERD symptoms in addition to its relation to physique mass index (BMI) and different risk factors among medical college students of Jeddah and Rabigh branches, King Abdul-Aziz University, Saudi Arabia.A cross-sectional research was carried out on the Faculty of Medicine in Rabigh, King Abdul-Aziz University, Saudi Arabia.

The research included 197 medical college students from Rabigh and Jeddah branches of the college. The research employed a Gastroesophageal Reflux Disease Questionnaire which is derived from a self-administered validated GERD questionnaire (GerdQ).

ResultsThe prevalence of GERD symptoms was 25.9%. The most frequent symptoms had been regurgitation and burning sensation. High BMI, household historical past, power drinks and fried meals had been discovered to be statistically important risk factors (p<0.05) by univariate evaluation.

However, the logistic regression for the prediction of GERD symptoms among medical college students confirmed that solely household historical past had a major correlation (p<0.05).GERD symptoms had been widespread in medical college students of King Abdulaziz University, Saudi Arabia.

Family historical past was discovered to be a major predictor of GERD symptoms. Effective instructional methods for teams with important risk factors of GERD should be applied.

Gastro-oesophageal reflux disease symptoms and associated risk factors among medical students, Saudi Arabia. — Gastro-oesophageal reflux disease symptoms and associated risk factors among medical college students, Saudi Arabia.

Association between private, medical and constructive psychological variables with somatization in college well being sciences college students.

Objective: To measure private, medical and psychological constructive and destructive variables and to find out their relation with somatization in a pattern of well being sciences college students.

Subjects and strategies: A complete of 594 (34.43%) of the 1725 well being science college students of a public college answered an internet survey with private and medical data in addition to the next psychological variables: phsychological well-being, 5 aspects mindfulness questionnaire (FFMQ), life satisfaction, despair, and tutorial stress. Additionally, the presence of 11 somatic symptoms and 11 illnesses over the past yr was measured.

Results: Most college students had been girls (74.06%) who had been 19.96 ± 4.28 years outdated. The world frequency of somatization within the earlier yr was 66.59%, and the presence of any measured disease 14.75%.

With the multivariate evaluation, self-acceptance was essentially the most associated variable (negatively) with somatization, adopted by the sum of illnesses, feminine gender, tutorial stress, smoking, and despair, in a mannequin with an R-value of 0.634, self-acceptance was additionally essentially the most associated variable (negatively) with despair, being this final essentially the most associated variable with tutorial stress.

Conclusions: After analyzing all variables thought of on this research, self-acceptance was essentially the most associated variable with somatization and despair; this highlights the significance of strengthening the acceptance of the self within the scholar inhabitants with a view to forestall these circumstances and their penalties.

Guessing right – whether and how medical students give incorrect reasons for their correct diagnoses.

Background: Clinical reasoning is without doubt one of the central competencies in on a regular basis scientific follow. Diagnostic competence is commonly measured based mostly on diagnostic accuracy. It is implicitly assumed {that a} correct analysis relies on a correct diagnostic course of, though this has by no means been empirically examined.

The frequency and nature of errors in students’ diagnostic processes in appropriately solved circumstances was analyzed on this examine.

Method: 148 medical students processed 15 digital affected person circumstances in inside drugs.

After every case, they have been requested to state their ultimate analysis and justify it. These explanations have been qualitatively analyzed and assigned to one of many following three classes: correct rationalization, incorrect rationalization and analysis guessed right.

Results: The correct analysis was made 1,135 instances out of two,080 diagnostic processes. The evaluation of the related diagnostic explanations confirmed that 92% (1,042) reasoning processes have been correct, 7% (80) have been incorrect, and 1% (13) of the diagnoses have been guessed right. Causes of incorrect diagnostic processes have been primarily an absence of pathophysiological data (50%) and an absence of diagnostic expertise (30%).

Conclusion: Generally, if the analysis is correct, the diagnostic course of can also be correct. The price of guessed diagnoses is kind of low at 1%. Nevertheless, about each 14th correct analysis relies on a false diagnostic rationalization and thus, a improper diagnostic course of. To assess the diagnostic competence, each the analysis end result and the diagnostic course of needs to be recorded.

Guessing right - whether and how medical students give incorrect reasons for their correct diagnoses. — Guessing right – whether and how medical students give incorrect reasons for their correct diagnoses.

Factors related to homophobia in medical students from eleven Peruvian universities.

The penalties of homophobia can have an effect on the integrity, psychological and bodily well being of gay people in society. There are few research in Peru which have evaluated homophobia within the medical scholar inhabitants.To set up the social, instructional and cultural components related to homophobia amongst Peruvian medical students.

A cross-sectional analytical examine was performed in 12 drugs faculties in Peru. Homophobia was outlined in response to a validated check, which was related to different variables. Statistical associations have been recognized.The lowest percentages of homophobic students (15-20%) have been discovered within the 4 universities in Lima, whereas universities within the inside of the nation had the very best percentages (22-62%).

Performing a multivariate evaluation, we discovered that the frequency of homophobia was decrease for the next variables: the feminine gender (PRa=0.74; 95% CI, 0.61-0.92; p=0.005), finding out at a college in Lima (PRa=0.57; 95% CI, 0.43-0.75; p<0.001), professing the Catholic faith (PRa=0.53; 95% CI, 0.37-0.76; p<0.001), understanding a gay (PRa=0.73; 95% CI, 0.60-0.90; p=0.003) and having handled a gay affected person (PRa=0.76; 95% CI, 0.59-0.98; p=0.036). I

n distinction, the frequency of homophobia elevated in male chauvinists (PRa=1.37; 95% CI, 1.09-1.72; p=0.007), adjusted by 4 variables.Homophobia was much less frequent in ladies, in those that examine within the capital, those that profess Catholicism and those that know/have handled a gay. In distinction, male chauvinists have been extra homophobic.

Programmable Molecular Scissors: Applications of a New Tool for Genome Editing in Biotech.

Targeted genome modifying is a sophisticated approach that allows exact modification of the nucleic acid sequences in a genome.

Genome modifying is often carried out utilizing instruments, reminiscent of molecular scissors, to chop a outlined location in a particular gene. Genome modifying has impacted numerous fields of biotechnology, reminiscent of agriculture; biopharmaceutical manufacturing; research on the construction, regulation, and performance of the genome; and the creation of transgenic organisms and cell strains.

Although genome modifying is used regularly, it has a number of limitations. Here, we offer an summary of well-studied genome-editing nucleases, together with single-stranded oligodeoxynucleotides (ssODNs), transcription activator-like effector nucleases (TALENs), zinc-finger nucleases (ZFNs), and CRISPR-Cas9 RNA-guided nucleases (CRISPR-Cas9).

To this finish, we describe the progress towards editable nuclease-based therapies and talk about the minimization of off-target mutagenesis. Future prospects of this difficult scientific area are additionally mentioned.

Programmable Molecular Scissors: Applications of a New Tool for Genome Editing in Biotech.

Next biotech crops: new traits, crops, builders and applied sciences for addressing international challenges.

Most of the genetically modified (GM) crops at present commercialized embody a handful of crop species (soybean, corn, cotton and canola) with agronomic characters (traits) directed in opposition to some biotic stresses (pest resistance, herbicide tolerance or each) and created by multinational firms. The similar crops with agronomic traits already available on the market right now will proceed to be commercialized, however there might be additionally a wider vary of species with mixed traits.

The timeframe anticipated for market launch of the subsequent biotech crops won’t solely rely on science progress in analysis and growth (R&D) in laboratories and fields, but additionally totally on how demanding regulatory necessities are in international locations the place advertising and marketing approvals are pending. Regulatory constraints, together with environmental and well being influence assessments, have elevated considerably in the previous many years, delaying approvals and rising their prices.

This has generally discouraged public analysis entities and small and medium dimension plant breeding firms from utilizing biotechnology and given choice to different applied sciences, not as stringently regulated. Nevertheless, R&D packages are flourishing in growing international locations, boosted by the need to satisfy the worldwide challenges which are meals safety of a booming world inhabitants whereas mitigating local weather change impacts.

Biotechnology is an instrument on the service of these imperatives and a wide selection of crops are at present examined for their excessive yield regardless of biotic and abiotic stresses. Many crops with increased water or nitrogen use effectivity, tolerant to chilly, salinity or water submergence are being developed. Food safety isn’t solely a query of amount but additionally of high quality of agricultural and meals merchandise, to be accessible and accessible for those who want it probably the most.

Many biotech crops (particularly staple meals) are subsequently being developed with dietary traits, reminiscent of biofortification in nutritional vitamins and metals. The most important worldwide seed firms proceed to be the biggest buyers in plant biotechnology R&D, and infrequently collaborate in the growing world with public establishments, personal entities and philanthropic organizations.

These partnerships are significantly current in Africa. In developed international locations, plant biotechnology can also be used for non-food functions, such because the pharmaceutical, biofuel, starch, paper and textile industries. For instance, crops are modified to particularly produce molecules with therapeutic makes use of, or with an improved biomass conversion effectivity, or producing bigger volumes of feedstocks for biofuels.

Various plant breeding applied sciences at the moment are used in your entire spectrum of plant biotechnology: transgenesis producing proteins or RNAi. Cisgenesis (transgenes remoted from a crossable donor plant) and intragenesis (transgenes originate from the identical species or a crossable species), null segregants are additionally used. To date, the subsequent technology precision gene modifying instruments are developed in fundamental analysis.

They embody: clustered usually interspaced brief palindromic repeats (CRISPR), oligonucleotide-directed mutagenesis (ODM), transcription activator-like results nucleases (TALENs) and zinc-finger nuclease (ZFN).